Conflicting interests: James Stone reports having received advisory and honorary commissions from Bayer Canada and Sanofi Canada. Dr. Stone is senior medical director, Cardiovascular Health and Stroke Strategic Clinical Network, Alberta Health Services; and member overall, Board of Directors, College of Physicians and Surgeons of Alberta. Jason Andrade reports receiving payments or fees from Medtronic, Biosense-Webster, Abbott, Bio-tronik, Bayer, Servier, and BMS-Pfizer. Simon Bacon reports receiving grants from Moderna, paid through Respiplus for the development of educational modules on vaccine hesitation and advisory and speaker commissions from Respiplus. Dr. Bacon has served on advisory committees for Bayer, Sanofi, Respiplus, and Lucilab, none of which are related to this article. Dr. Bacon also holds a patient-oriented research mentoring chair (SMC-151518) from the Canadian Institutes of Health Research (CIHR) and a chair from the Fonds de recherche du Québec (251618 and 309815). Harpreet Bajaj reports receiving grants from Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Gilead, Janssen, Kowa Pharmaceuticals, Merck, Novo Nordisk, Pfizer, Sanofi and Tricida; and tuition fees from Eli Lilly and Novo Nordisk. Mark Gelfer reports receiving advisory commissions from Telus Health Care Centers and holding an unpaid role as chairman of the board of GenXys Health Care Systems, in which Dr. Gelfer also holds stock options. Jeffrey Habert reports receiving advisory commissions from MDBriefcase, Liv, MedPlan, Master Clinician Alliance, Academy, Bridge, Seacourses, Thrombosis Canada, Meducom, Antibody, Canadian Heart Research Center, CTC Communications, STA Healthcare Communications, Canadian Collaborative Research Network, CPD Network, Telus Health, EOCI Pharmacomm and Operatic. Dr. Habert has also received honoraria from Pfizer, Amgen, BMS, Bayer, Boehringer Ingelheim, Eli Lilly, GlaxoSmithKline, Purdue, Bausch, Allergan, AbbVie, AstraZeneca, Novartis, Lundbeck, Canadian Cardiovascular Health Education Program (CHEP +), Novo Nordisk , Janssen, Eisai, HLS, Otsuka, Sunovion and Jazz. Dr. Habert was the previous co-chair of Thrombosis Canada Clinical Guides (2018–2021). Karim Keshavjee reports having received advisory commissions from McMaster University, Demers Professional Corporation and Regulations. Darlene Kitty reports receiving teaching salaries from the University of Ottawa School of Medicine and McGill University School of Medicine for occasional lectures and travel support as director of the University of Ottawa School of Medicine’s Indigenous Program . Dr. Kitty is the chair of the Indigenous Health Committee, College of Family Physicians of Canada. David Lau reports receiving grants from Novo Nordisk; consulting fees from Amgen, Bayer, Boehringer Ingelheim, CME at Sea, HLS Therapeutics, Eli Lilly, Novo Nordisk and Viatris; honoraries from Amgen, Bayer, Boehringer Ingelheim, CME at Sea, HLS Therapeutics, Eli Lilly and Novo Nordisk; and payment for expert testimony from the Canadian Medical Protective Association. Dr. Lau has held leadership roles with Obesity Canada and the Canadian Association of Bariatric Physicians and Surgeons. Laurent Macle reports receiving grants and fees from BMS-Pfizer, Servier and Bayer. Michael McDonald reports receiving consulting fees from Boehringer Ingelheim and fees from Novartis and Servier. Dr. McDonald also participated in the data safety monitoring committee for the IVVE study. Kara Nerenberg reports membership in clinical practice guidelines committees for the Heart and Stroke Foundation, Obesity Canada, Hypertension Canada, Diabetes Canada, and the Society of Obstetricians and Gynecologists of Canada. Glen Pearson reports that he has received advisory commissions from Novartis Canada as a participant in the advisory committee. Alexandre Poppe reports that he has received a scholarship from Stryker and an honorarium from Pfizer-BMS. Dr. Poppe also participated in a data safety monitoring committee for the FLOW study of fluoxetine after stroke and the safety committee for Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke (AcT study) of tenecteplase for stroke. acute. Dr. Poppe received support from the scholarship program from Servier. Diana Sherifali reports receiving personal funding through her Heather M. Arthur Population Health Institute / Hamilton Health Sciences Chair in Interprofessional Health Research. Peter Selby reports receiving grants from the Ontario Ministry of Health and Pfizer (Global Research Awards for Nicotine Dependence). Dr. Selby has also participated in the C-CHANGE guideline panel since 2010. Eric Smith reports that he has received advisory commissions from Bayer, Biogen, Alnylam and Cyclerion. Sol Stern reports receiving consulting fees and honoraria from MDBriefcase.com and Sea Courses Inc. George Thanassoulis reports receiving grants, consulting fees and honoraria from Amgen, Sanofi, Novartis and Silence. Dr. Thanassoulis was also a member of the CCS Dyslipidemia Guidelines Committee. Kristin Terenzi reports receiving fees for consultancy committees, conference event fees and meeting attendance support from AstraZeneca, Boehringer Ingelheim, Astellas, Allergan, Amgen, Aspen, Bayer, Lilly, Lundbeck, AbbVie, Aralez, GSK , Merck, Novo Nordisk, Pfizer and Novartis. Karen Tu reports receiving grants (institution payments) from CIHR, St. Michael’s Hospital Foundation, The College of Family Physicians of Canada, Foundation for Advancing Family Medicine, Canadian Medical Association Foundation, North York General Hospital Exploration Fund, Heart and Stroke Foundation of Canada, Heart and Stroke Foundation of Ontario, United States Department of Defense, University of Toronto – Department of Family and Community Medicine, MaRS Innovation Fund, Canadian Dermatology Foundation, Canadian Rheumatology Association (Canadian Initiative for Outcomes in Rheumatology Care), PSI Foundation, Cancer Care Ontario, Toronto Rehab Institute Chair Fund, UTOPIAN, Arthritis Society, MS Society of Canada, The Canadian Vascular Network, Ontario SPOR Support Unit Targeted IMPACT Award and Rathlyn Foundation. Dr. Tu received a Research Scholar Award from the Department of Family and Community Medicine at the University of Toronto. Jacob Udell reports receiving grants from Boehringer Ingelheim, Janssen, Sanofi and Novartis; and fees from AstraZeneca, GlaxoSmithKline and Sanofi. Dr. Udell has also participated in advisory committees for Boehringer Ingelheim, Sanofi and Novartis. Sean Virani reports receiving grants from Abbott, Amgen, AstraZeneca, Boehringer Ingelheim, Bayer, Novartis, Servier, Otsuka and Medtronic; consulting fees from Abbott, Amgen, AstraZeneca, Boehringer Ingelheim, Bayer, Novartis, Seriver and Otsuka; and fees from Abbott, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Bayer, Novartis, Servier, Otsuka and Medtronic. Dr. Virani has also participated in data security monitoring committees or advisory committees for Abott and Medtronic. Richard Ward reports having received consulting fees from Eisai and Lilly-Boehringer Ingelheim and payments or fees from Boehringer Ingelheim, AstraZeneca, Janssen, Amgen, Lilly, Pfizer and Takeda. Dr. Ward is also director of the Alberta Medical Association. Sean Wharton reports receiving grants and fees from Novo Nordisk, Eli Lilly, Bausch Health Canada and Boehringer Ingelheim; he has participated in data security monitoring committees for Novo Nordisk, Eli Lilly, Bausch Health Canada and Boehringer Ingelheim; and has received equipment, medical papers or other services from Novo Nordisk, Eli Lilly, and Bausch Health Canada. Dr. Wharton has also played a leadership role in The Obesity Society and Obesity Canada. Jennifer Zymantas reports receiving an honorarium from Pfizer for a moderating role during anticoagulation-related intervention commitments. Diane Hua-Stewart holds the position of director of CHEP +. Peter Liu reports receiving grants from Genome Canada, the Heart and Stroke Foundation, and CIHR. Dr. Liu holds a patent for IGFBP7 as a biomarker for heart failure and is scientific director of the University of Ottawa Heart Institute. Sheldon Tobe reports receiving an unlimited grant for the KMH clinic and in-kind support for the Zero to Five study, paid to the Sunnybrook Research Institute; consultancy fees from AstraZeneca; and payment for the CHEP + education program from Amgen, Astra-Zeneca, BMS, Bayer, Boehringer Ingelheim, Janssen, Lilly, Novartis, Novo Nordisk, Pfizer, and Sanofi Genzyme. Dr. Tobe also serves as a volunteer with the American Hypertension Specialists Certification Program. No other competing interests have been declared.

Leave a Reply

Your email address will not be published. Required fields are marked *